Correction: Vitamin D Metabolic Pathway Genes and Pancreatic Cancer Risk
نویسندگان
چکیده
Hannah Arem, Kai Yu, Xiaoqin Xiong, Kristin Moy, Neal D. Freedman, Susan T. Mayne, Demetrius Albanes, Laufey T. Amundadottir, Alan A. Arslan, Melissa Austin, William R. Bamlet, Laura Beane-Freeman, Paige Bracci, Federico Canzian, Stephen J Chanock, Michelle Cotterchio, Eric J. Duell, Steve Gallinger, GrahamG. Giles, Michael Goggins, Phyllis J. Goodman, Patricia Hartge, Manal Hassan, Kathy Helzlsouer, Brian Henderson, Elizabeth A. Holly, Robert Hoover, Eric J. Jacobs, Aruna Kamineni, Alison Klein, Eric Klein, Laurence N. Kolonel, Donghui Li, Núria Malats, Satu Männistö, Marjorie L. McCullough, Sara H. Olson, Irene Orlow, Ulrike Peters, Gloria M. Petersen, Miquel Porta, Gianluca Severi, Xiao-Ou Shu, Stephen Van Den Eeden, Kala Visvanathan, Emily White, Herbert Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Geoffrey S. Tobias, Dennis Maeder, Michelle Brotzman, Harvey Risch, Joshua N. Sampson, Rachael Z. Stolzenberg-Solomon
منابع مشابه
Vitamin D Metabolic Pathway Genes and Pancreatic Cancer Risk
Evidence on the association between vitamin D status and pancreatic cancer risk is inconsistent. This inconsistency may be partially attributable to variation in vitamin D regulating genes. We selected 11 vitamin D-related genes (GC, DHCR7, CYP2R1, VDR, CYP27B1, CYP24A1, CYP27A1, RXRA, CRP2, CASR and CUBN) totaling 213 single nucleotide polymorphisms (SNPs), and examined associations with pancr...
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Recent studies of 25-hydroxyvitamin D (25(OH)D) levels and pancreas cancer have suggested a potential role of the vitamin D pathway in the etiology of this fatal disease. Variants in vitamin-D related genes are known to affect 25(OH)D levels and function and it is unknown if these variants may influence pancreatic cancer risk. The association between 87 single nucleotide polymorphisms (SNPs) in...
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Background & objective: Ovarian cancer mortality is associated with lower regional sunlight exposure. Vitamin D and its metabolites are best known for their action in calcium and bone metabolism. However, epidemiological studies have suggested that an increased ovarian cancer risk is associated with decreased production of vitamin D. The vitamin D signaling pathway is involved in a wide variety...
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Background and Objectives: Evidence indicate relationships between the sunlight exposure, vitamin D status and non-melanoma skin cancer (NMSC) risk. Vitamin D receptor (VDR) polymorphisms have been linked to metabolic changes in insulin resistance and various cancers. The purpose of this study is to investigate relationships between the sunlight exposure and the NMSC risk. Furthermore, relation...
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Background and Objectives: There is convincing evidence that subjects concomitantly affected by type 2 diabetes (T2D) and metabolic syndrome (MeS) are at greater risk for cardiovascular disease (CVD). Many metabolic derangements in T2D might be attributed to poor vitamin D status. The purpose of this study was to investigate the associations among vitamin D status, MeS and glycemic status in su...
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BACKGROUND Pancreatic cancer is the fourth leading cause of cancer death in the U.S. and the etiology of this highly lethal disease has not been well defined. To identify genetic susceptibility factors for pancreatic cancer, we conducted pathway analysis of genome-wide association study (GWAS) data in 3,141 pancreatic cancer patients and 3,367 controls with European ancestry. METHODS Using th...
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